G Edan Selected Research

Mitoxantrone (Novantrone)

6/2022	Ten-year follow-up after mitoxantrone induction for early highly active relapsing-remitting multiple sclerosis: An observational study of 100 consecutive patients.
6/2018	Induction or escalation therapy for patients with multiple sclerosis?
12/2011	Mitoxantrone prior to interferon beta-1b in aggressive relapsing multiple sclerosis: a 3-year randomised trial.
7/2011	Long-term safety profile of mitoxantrone in a French cohort of 802 multiple sclerosis patients: a 5-year prospective study.
12/2008	[Use of mitoxantrone in early multiple sclerosis with malignant disease course. Observational study in 30 patients with clinical and MRI outcomes after one year].
2/2006	[Mitoxantrone as induction therapy in aggressive relapsing remitting multiple sclerosis: a descriptive analysis of 100 consecutive patients].
11/2005	Mitoxantrone in the treatment of multiple sclerosis.
1/2005	Acute demyelination: an insight into the effect of mitoxantrone on CNS lesions.
11/2004	Consensus statement concerning cardiotoxicity occurring during haematopoietic stem cell transplantation in the treatment of autoimmune diseases, with special reference to systemic sclerosis and multiple sclerosis.
8/2004	Predictive parameters of mitoxantrone effectiveness in the treatment of multiple sclerosis.

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G Edan Research Topics

Disease

29	Multiple Sclerosis 06/2022 - 01/2000
6	Relapsing-Remitting Multiple Sclerosis 06/2022 - 02/2006
4	Neoplasms (Cancer) 11/2005 - 10/2000
4	Cardiotoxicity 11/2004 - 03/2000
3	Demyelinating Diseases (Demyelinating Disease) 03/2010 - 10/2003
3	Genetic Predisposition to Disease (Genetic Predisposition) 10/2003 - 01/2000
2	Autoimmune Diseases (Autoimmune Disease) 06/2018 - 11/2004
2	Chronic Progressive Multiple Sclerosis 04/2016 - 08/2010
2	Leukemia 09/2002 - 09/2002
1	Optic Nerve Diseases (Optic Neuropathy) 10/2016
1	Optic Neuritis (Retrobulbar Neuritis) 10/2016
1	Hypersensitivity (Allergy) 01/2016
1	Urinary Retention 08/2010
1	Spinal Cord Diseases 06/2010
1	Ataxia (Dyssynergia) 06/2010
1	Nephrotic Syndrome (Syndrome, Nephrotic) 06/2010
1	Iron Overload 06/2010
1	Disease Susceptibility (Diathesis) 04/2008
1	Parkinson Disease (Parkinson's Disease) 08/2006
1	Fatigue 04/2005
1	Systemic Scleroderma (Systemic Sclerosis) 11/2004
1	Disease Progression 08/2004
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 09/2002
1	Juvenile Myoclonic Epilepsy 12/2000
1	Stroke (Strokes) 10/2000
1	Kidney Neoplasms (Kidney Cancer) 10/2000
1	Cerebral Infarction 10/2000

Drug/Important Bio-Agent (IBA)

15	Mitoxantrone (Novantrone)FDA LinkGeneric 06/2022 - 03/2000
5	Interferon beta-1b (Betaseron)FDA Link 04/2016 - 10/2006
3	InterferonsIBA 04/2016 - 05/2001
3	chlorbensideIBA 12/2011 - 02/2006
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 11/2004 - 03/2000
2	Natalizumab (Tysabri)FDA Link 01/2022 - 09/2011
2	CytokinesIBA 08/2010 - 01/2000
2	HLA Antigens (Human Leukocyte Antigens)IBA 09/2008 - 04/2008
2	HLA-DRB1 Chains (HLA DRB1)IBA 09/2008 - 02/2003
2	Azathioprine (Imuran)FDA LinkGeneric 09/2001 - 03/2000
2	Methotrexate (Mexate)FDA LinkGeneric 09/2001 - 03/2000
2	Interferon-betaIBA 05/2001 - 03/2000
1	Methylprednisolone FDA LinkGeneric 03/2022
1	Fingolimod Hydrochloride (FTY720)FDA Link 01/2022
1	Alemtuzumab (Campath)FDA Link 06/2018
1	Immunosuppressive Agents (Immunosuppressants)IBA 06/2018
1	Cladribine FDA LinkGeneric 06/2018
1	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2016
1	Vitamin D FDA LinkGeneric 01/2016
1	VaccinesIBA 01/2016
1	Neutralizing AntibodiesIBA 08/2011
1	Amino Acids FDA Link 08/2010
1	PI 2301IBA 08/2010
1	CollagenIBA 08/2010
1	CopperIBA 06/2010
1	Antigen-Antibody Complex (Immune Complex)IBA 03/2010
1	Modafinil (Provigil)FDA Link 04/2005
1	AnthracyclinesIBA 11/2004
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 10/2003
1	HLA-DR Antigens (HLA-DR)IBA 02/2003
1	Cytotoxins (Cytolysins)IBA 09/2002
1	Interferon beta-1a FDA Link 05/2001
1	Lamotrigine (Lamictal)FDA LinkGeneric 12/2000
1	Interleukin-2 (IL2)IBA 10/2000
1	Interferon-alpha (Interferon Alfa)IBA 10/2000
1	Immunomodulating AgentsIBA 03/2000
1	AntigensIBA 01/2000
1	Cytokine Receptors (Cytokine Receptor)IBA 01/2000
1	Genetic Markers (Genetic Marker)IBA 01/2000

Therapy/Procedure

10	Therapeutics 06/2018 - 10/2000
1	Deep Brain Stimulation 08/2006
1	Operative Surgical Procedures 08/2006
1	Cesarean Section (Caesarean Section) 01/2006
1	Neurological Rehabilitation 02/2005
1	Stem Cell Transplantation 11/2004
1	Transplantation 11/2004
1	Radiotherapy 09/2002